α-Eleostearic Acid (9Z11E13E-18:3) Is Quickly Converted to Conjugated Linoleic Acid (9Z11E-18:2) in Rats

Jacaric acid is rapidly metabolized to conjugated linoleic acid in rats.

We have shown previously that jacaric acid (JA; 8c,10t,12c-18:3), which has a conjugated triene system, has a strong anti-tumor effect. However, the characteristics of absorption and metabolism of JA have yet to be determined in vivo, and the details of absorption and metabolism of JA in the small intestine are particularly unclear. This information is required for effective use of JA in humans...

Conjugated Linoleic Acid Targets

Conjugated Linoleic Acid

Conjugated linoleic acid, better known as CLA, is a fatty acid derived from the required nutrient, linoleic acid. The major structural difference between linoleic acid (an 18 carbon, polyunsaturated fatty acid) and CLA, is that linoleic acid has double bonds at carbons 9 and 12 in a cis configuration (methylene interrupted), while CLA has numerous isomers without methylene interrupted conjugate...

Conjugated linoleic acid pork research.

The driving force behind most conjugated linoleic acid (CLA) research in swine has been related to potential improvements in animal production. Early work that used rodent models indicated that feeding CLA could potentially reduce body fat, increase lean content, increase growth rate, and improve feed conversion efficiency. Producer-backed funding organizations were, therefore, receptive to pro...

Conjugated Linoleic Acid – an Update

An article we wrote for the 1998 Illinois Dairy Report (Can Milk Fat be Beneficial to Your Health?) provided a brief description of conjugated linoleic acid (CLA), a minor component of milk fat. Briefly, CLA is a fatty acid that is synthesized in the rumen during biohydrogenation of linoleic acid (C18:2), the predominant fatty acid in vegetable oils. The pathway of biohydrogenation is C18:2 ? C...